Sermorelin is a bioidentical hormone peptide that mimics the effects of Growth Hormone Releasing Hormone (GHRH). GHRH’s function is to stimulate the release of Human Growth Hormone (hGH). Sermorelin contains the first 29 amino acids of GHRH, which is what makes the medication bioidentical. As we get older, hGH levels decrease, leading to symptoms often associated with aging. By triggering the secretion of hGH, Sermorelin has shown success in restoring hGH to youthful levels.
Human Growth Hormone (hGH) is responsible for many functions in the body. These include healing and recovery, regulating body composition, cell regeneration, and growth and development.
HGH levels are at their highest in adolescence. Levels gradually decrease over time, until they fall to roughly one-tenth of peak levels by the time we turn 55. The decrease can lead to fat gain, difficulty building muscle, slowed healing, difficulty recovering after exercise, and other life-disrupting symptoms. Sermorelin is used in Peptide Therapy to replenish hGH levels and
relieve these symptoms.
Sermorelin is an injection, and it comes in a glass vial. The medication is lyophilized, or dried, and will need to be reconstituted to be injected. Each Sermorelin vial comes with a bottle of bacteriostatic water, or sterilized water to mix with the powdered medication. The vial is vacuum sealed by the pharmacy for your protection and for the preservation of the hormone peptide.
Administration and storage instructions will be provided with your prescription.
Sermorelin is injected into the body fat, subcutaneously, using a very small needle similar to what a diabetic uses to inject insulin. Injections are typically prescribed every day, or Monday-Friday with no injections on the weekends depending on your protocol.
The best time to take Sermorelin is prior to bedtime. HGH is primarily released during sleep, and it’s most beneficial to the body’s recovery and repair process during this time. Sermorelin may cause sleepiness or drowsiness, as well, so it’s best to take it at night.
HGH levels are complex to monitor in the body. Because of this, it’s best to order a number of tests that will help your provider understand how your body produces and uses hGH.
Patients typically report improved sleep within the first few weeks of therapy, along with increased energy levels and improved mood. After 3-6 months of therapy, patients typically report significant body changes, such as increased muscle tone and a leaner physique. Over time, many patients also notice a significant improvement in skin tone and health. Like most peptide hormones, Sermorelin has a “loading” period of 3-6 months before patients notice the effects. Sermorelin is also eliminated quickly from the body. That means frequent injections are necessary to maintain hGH levels.
Ultimately, Sermorelin triggers a chain reaction of biological processes, and these result in elevated and sustained hGH levels. It takes time to optimize levels and see the full benefit.
No, Sermorelin doesn’t need to be taken indefinitely. Similar to synthetic hGH, Sermorelin needs to be injected daily at first. But unlike synthetic hGH, Sermorelin can be decreased and potentially stopped once patients reach sustained optimal hGH levels. At that point, your provider will likely switch you to a maintenance protocol.